BioML Build-Off · Day 003 of 300

Immunoglobulin Locus Explorer

Three AI coding agents, one one-sentence brief, three independent builds. Open each below and explore the same loci — everything runs locally in your browser.

The brief (identical for all three): “A standalone page giving a pleasant overview of the immunoglobulin locus in mouse and human (click to toggle), zooming all the way down to codons and nucleotides, with homologous V regions coloured alike and easy zoom so the user doesn’t get lost — plus a guided-but-escapable mode to pick a V/D/J (heavy) or V/J (light) and see how it comes together, with N- and P-nucleotide addition. User: a biology grad student.”

Head-to-head testing pending — shared this build gallery with the group first

⚠ On fairness: Claude built one of the three tools and drafted the test strategy, so it will not be the neutral judge — the plan in TEST-STRATEGY.md is frozen and signed off by a non-competitor before any tool is scored. For now this page is just a gallery of the three builds.

🗳 Tried all three? Vote for your favourite — the tally updates live under each build.

Claude

Anthropic Claude Opus 4.8 · Claude Code

Semantic-zoom Canvas browser (locus → segment → RSS/exon → nucleotide + protein) with a guided V(D)J recombinator: live trimming, P/N addition, CDR3 and productivity readout.

▶ Open Claude’s build

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Agy

Google Gemini 3.5 Flash (High) · Antigravity

Comparative genomic browser with a step-by-step V(D)J recombination wizard — RSS cleavage, P- and N-addition, nibble-and-ligate, and translation.

▶ Open Agy’s build

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Codex

OpenAI GPT-5.5 (Medium) · Codex CLI

Immunoglobulin locus explorer with drill-down to the nucleotide level and a guided segment-selection flow for assembling a rearrangement.

▶ Open Codex’s build

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One vote per browser. The live tally is kept by Abacus, a free public counter — a friendly group poll, not a secure ballot. The only thing sent is a +1 for the build you pick; no personal data. If you’re offline the builds still open, just without the count.

About this day · Test strategy (frozen plan) · The build brief
Part of the BioML Build-Off — a 300-day public benchmark. Reader-facing labels name the model; claude/agy/codex are internal folder ids.